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EGF antibody [S-21]

Cat. No. GTX18630

Host

Mouse

Clonality

Monoclonal

Clone Name

S-21

Isotype

IgG1

Application

ELISA

Reactivity

Human
Package
250 μg ($399)

APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

134 kDa. ( Note )

Product Note

Detects endogenous and recombinantly expressed human EGF. Does not cross-react with other human cytokines such as IL1 beta, IL8, MCAF, TGF beta and SAA.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human). 6kDa, 53 amino acid residues.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

epidermal growth factor , HOMG4 , URG

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Database

Research Area

REFERENCE

There are currently no references for EGF antibody [S-21] (GTX18630). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399
Custom Conjugations